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Doctor
on Call: Trans Fatty Acids
by Jeffrey Rehm, MD
I have three
children who love doughnuts. We will occasionally indulge ourselves
for breakfast and get a box of them. In December 2006, New York
City board of health voted to ban trans fatty acids from restaurants
and fast food establishments. Why? And what does this have to do
with our doughnuts?
Dietary fats
are perceived to be associated with heart disease and obesity among
other things. Certain fats increase total cholesterol and LDL cholesterol
which can increase cholesterol buildup (plaques) and inflammation
within the coronary arteries increasing the chance of a plaque rupturing
into the coronary artery causing a heart attack, which may lead
to death. The logical reaction is to avoid fats, right? Wrong! The
evidence is weak that a high fat diet causes heart disease or even
obesity. Not all fats are created equal.
What types of fat are there? Saturated fatty acids (SFA) are chiefly
from animal products (red meat, milk products). SFA increase total
serum cholesterol which, in turn, increase coronary events and mortality
slightly. A reduction in SFA decreases total serum cholesterol and
LDL-cholesterol and decreases coronary heart disease.
Monounsaturated
fatty acids (MFA) found in olive and canola oil, tend to decrease
LDL-cholesterol, triglycerides (also associated with coronary heart
disease) and maintain HDL-cholesterol ("good" cholesterol,
protective of coronary heart disease). In addition to the cholesterol
benefits, MFA also tend to have some beneficial effects on the blood
vessels helping to protect against coronary heart disease. This
tends to be the basis for the recommendation of a "Mediterranean"
diet.
Polyunsaturated
fatty acids (PFA) come in two varieties, linoleic acid and alpha-linolenic
acid. Linoleic acid is found in safflower, sunflower and corn oils.
Compared with saturated fatty acids, the tend to lower LDL-cholesterol,
HDL-cholesterol and triglycerides. The net effect appears to be
a slight benefit in reducing coronary heart disease.
Alpha-linolenic
acid is found in fish oils. These oils tend to have less of an effect
on cholesterol, but appear to decrease platelet aggregation (clumping
of a blood product necessary for a heart attack), triglyceride levels
and reduce cholesterol buildup with in the coronary blood vessels.
These fatty acids appear to be cardioprotective.
Trans fatty
acids (TFA) may be found in nature but most are industrially manufactured
by pumping hydrogen gas into liquid fat (partial hydrogenation)
creating fats that will stay solid at room temperature and last
forever. These are found in pie crusts, cookies, cakes, fried foods
like fried chicken, french fries (freedom fries anyone?) and, yes,
doughnuts! TFA raise the LDL-cholesterol a little, but lower the
HDL-cholesterol a lot. Even saturated fatty acids don't interfere
with the beneficial effects of HDL-cholesterol. In addition, TFA
interfere with the beneficial effects of omega-3 fatty acids. In
one study, for each 2% increase in energy from TFA, the incidence
of coronary heart disease doubles! In other words, these are really
bad for you.
Well what about
our doughnuts? At present, they contain TFA. There are substitutes
for most things. Yeast doughnuts may be duplicated with safer ingredients,
but cake doughnuts and fried dough products are more difficult to
duplicate. How does the New York legislation affect our Fredericksburg
doughnuts you ask? Because of the legislation, many companies are
actively researching alternative fat substitutes (Dunkin' Doughnuts,
Au Bon Pan and Ruby Tuesday). Once a satisfactory solution is found
in New York, most likely recipes and fat substitutions will occur
nationwide. Until that time, make sure you read labels on foods
(June 2006, FDA requires trans fat labeling) and ask at your favorite
restaurant.
As an addition to a previous article on allergy shots, there is
good news! For most patients a response to their allergy shots typically
occurs in months, and certainly within the first year. In fact,
in Europe they at times give allergy shots only for a few months
before the pollen season, and this works for the season though doesn't
result in permanent relief. Often if the allergy injections continue
monthly for the full 3-5 year period the improvement will last for
years after the allergy shots have ceased. It is the only treatment
that has been shown to change the natural course of the disease.
Dr.
Jeffrey Rehm, father of three, is a pulmonologist at both Mary Washington
Hospital and
521 Park Hill Drive. Phone is (540)899-1615.
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